Collaborative Stage for TNM 7 - Revised 10/21/2010 [ Schema ]
CS Site-Specific Factor 5
Chromosome 1p: Loss of Heterozygosity (LOH)
- Note 1: This is a special molecular diagnostic test performed on tumor tissue to identify loss of genetic material normally found on the short arm of one of the patient's two copies of chromosome 1. A normal cell will contain two complete copies of each chromosome, one from each parent, and this normal state is termed heterozygous. Loss of heterozygosity (LOH) is an abnormal state reflecting damage to the chromosome.
- Note 2: Other terms for LOH include gene deletion and allelic loss.
- Note 3: For brain tumors, tests for LOH of chromosomes 1p and 19q may be performed at the same time and reported on a single report. See also CS Site-Specific Factor 6.
|010||Test positive for loss of heterozygosity (LOH)|
|020||Test negative for LOH|
|888||OBSOLETE DATA CONVERTED V0200|
See code 988
Not applicable for this site
|988||Not applicable: Information not collected for this case|
(May include cases converted from code 888 used in CSv1 for "Not applicable" or when the item was not collected. If this item is required to derive T, N, M, or any stage, use of code 988 may result in an error.)
|997||Test ordered, results not in chart|
|998||No histologic examination of primary site|
Test not done (test not ordered and not performed)
|999||Unknown or no information|
Not documented in patient record