Collaborative Stage

Note 1: Of the three tumor markers, lactate dehydrogenase (LDH) is the least specific for testicular cancer and is more of a determinant of bulky or disseminated disease. Although recommended to be tested, LDH may not be routinely performed, especially if the primary is localized.
Note 2: Record the range of the LDH test as documented in the patient record after orchiectomy and prior to further treatment.
Note 3: If the initial post-orchiectomy LDH test remains elevated, review the subsequent tests until normalization or plateau occurs and use that test to code this field. See Part I for further explanation of serum tumor marker half life.
Note 4: If the post-orchiectomy LDH test is unknown but the preorchiectomy LDH test was normal, use code 990.
Note 5: If the post-orchiectomy LDH test is unavailable but a physician's statement of the result is documented, use codes 991-993.
Note 6: For rare cases that are treated prior to orchiectomy or an orchiectomy is not performed, code the initial LDH range in this field and not in CS Site-Specific Factor 10.

Code	Description
000	Within normal limits (S0)
010	Range 1 (S1) less than 1.5 x N (Less than 1.5 times the upper limit of normal for LDH)
020	Range 2 (S2) 1.5 to 10 x N (Between 1.5 and 10 times the upper limit of normal for LDH)
030	Range 3 (S3) greater than 10 x N (Greater than 10 times the upper limit of normal for LDH)
988	Not applicable: Information not collected for this case (If this information is required by your standard setter, use of code 988 may result in an edit error.)
990	Postorchiectomy LDH unknown but preorchiectomy LDH was normal
991	Postorchiectomy LDH stated to be still elevated
992	Postorchiectomy LDH unknown but post-orchiectomy serum tumor markers NOS stated to be normal
993	Postorchiectomy LDH unknown but postorchiectomy serum tumor markers NOS stated to be still elevated Stated as Stage IS
997	Test ordered, results not in chart
998	Test not done (test not ordered and not performed)
999	Unknown or no information Not documented in patient record

CS Site-Specific Factor 16
Post-Orchiectomy Lactate Dehydrogenase (LDH) Range