Collaborative Stage

Note 1: For rectosigmoid, ignore intraluminal extension to adjacent segment(s) of colon and rectum; code depth of invasion or extra-rectosigmoidal spread as indicated.
Note 2: Codes 600 - 750 are used for contiguous extension from the site of origin. Discontinuous involvement is coded in CS Mets at DX.
Note 3: Tumor that is adherent to other organs or structures, macroscopically, is classified cT4b; If tumor is present in adhesion(s) upon microscopic examination, the tumor is classified as pT4b. Use code 565 for macroscopic adhesions if no pathologic confirmation, and for pathologically confirmed tumor in adhesions. However, if no tumor is present in adhesion(s) upon microscopic examination, the classification is based upon extent of tumor invasion into or through the wall; use codes 000 - 163, 200, 210, 400, 415, 455, 458, 500, and 555 as appropriate to describe the microscopically confirmed depth of tumor invasion for these cases. Use codes 610-800 to code invasion of underlying structures from the adherent tumor.
Note 4: High grade dysplasia and severe dysplasia are generally not reportable in cancer registries but, if a registry does collect these, codes 000 or 050 should be used.

Code	Description	TNM 7 Map	TNM 6 Map	SS77 Map	SS2000 Map
000	In situ, intraepithelial, noninvasive	Tis	Tis	IS	IS
050	(Adeno)carcinoma, noninvasive, in a polyp or adenoma	Tis	Tis	IS	IS
100	Invasive tumor confined to mucosa, NOS including intramucosal, NOS	Tis	Tis	L	L
110	Invades lamina propria, including lamina propria in the stalk of a polyp	Tis	Tis	L	L
120	Confined to and not through the muscularis mucosae, including muscularis mucosae in the stalk of a polyp.	Tis	Tis	L	L
130	Confined to head of polyp, NOS	T1	T1	L	L
140	Confined to stalk of polyp, NOS	T1	T1	L	L
150	Invasive tumor in polyp, NOS	T1	T1	L	L
160	Submucosa (superficial invasion), including submucosa in the head or stalk of a polyp	T1	T1	L	L
165	For rectum: Tumor invading submucosa with intraluminal extension to colon and/or anal canal/anus	T1	T1	L	L
170	Stated as T1 with no other information on extension	T1	T1	L	L
200	Muscularis propria invaded	T2	T2	L	L
210	For rectum: Tumor invading muscularis propria with intraluminal extension to colon and/or anal canal/anus	T2	T2	RE	L
250	Stated as T2 with no other information on extension	T2	T2	L	L
300	Confined to rectosigmoid junction, NOS Confined to rectum, NOS Localized, NOS	T1	T1	L	L
400	Extension through wall, NOS Invasion through muscularis propria or muscularis, NOS Non-peritonealized perirectal tissues invaded Perimuscular tissue invaded Subserosal tissue/(sub)serosal fat invaded Transmural, NOS	T3	T3	L	L
410	OBSOLETE DATA CONVERTED V0203 See code 470 Stated as T3 with no other information on extension	ERROR	ERROR	ERROR	ERROR
415	For rectum: Tumor invading through muscularis propria with intraluminal extension to colon and/or anal canal/anus	T3	T3	RE	L
420	OBSOLETE DATA CONVERTED V0203 See code 458 Fat, NOS	ERROR	ERROR	ERROR	ERROR
450	OBSOLETE DATA RETAINED AND REVIEWED V0203 Extension to anus from rectum recoded based on intraluminal versus extraluminal extension See codes 165, 210, 415, 455, and 610 Adjacent (connective) tissue: For all sites: Perirectal fat For rectosigmoid: Mesentery (including mesenteric fat, mesocolon) Pericolic fat For rectum: Extension to anus Rectovaginal septum	T3	T3	RE	RE
455	Adjacent (connective) tissue: For all sites: Perirectal fat For rectosigmoid: Mesentery (including mesenteric fat, mesocolon) Pericolic fat For rectum: Rectovaginal septum	T3	T3	RE	RE
458	Fat, NOS	T3	T3	RE	RE
460	OBSOLETE DATA RETAINED AND REVIEWED V0203 See Note 3, codes 565, 570 Adherent to other organs or structures but no tumor found in adhesion(s)	T3	T3	RE	RE
470	Stated as T3 with no other information on extension	T3	T3	RE	RE
490	OBSOLETE DATA CONVERTED V0203 See code 900 Stated as T4[NOS] with no other information on extension	ERROR	ERROR	ERROR	ERROR
500	Invasion of/through serosa (mesothelium) (visceral peritoneum) Tumor penetrates visceral peritoneum	T4a	T4	RE	RE
550	OBSOLETE DATA RETAINED AND REVIEWED V0203 See codes 555, 610 (500) with [(420) or (450)]	T4a	T4	RE	RE
555	500 + (165, 210, 415, or 458)	T4a	T4	RE	RE
560	Stated as T4a with no other information on extension	T4a	T4	RE	RE
565	Adherent to other organs or structures clinically with no microscopic examination Tumor found in adhesion(s) if microscopic examination performed	T4b	T4	RE	RE
570	Adherent to other organs or structures, NOS	T4b	T4	RE	RE
600	OBSOLETE DATA CONVERTED V0203 See code 610 Rectosigmoid: Cul de sac (rectouterine pouch) Pelvic wall Small intestine Rectum: Bladder for males only Cul de sac (rectouterine pouch) Ductus deferens Pelvic wall Prostate Rectovesical fascia for male only Seminal vesicle(s) Skeletal muscle of pelvic floor Vagina	ERROR	ERROR	ERROR	ERROR
610	For rectosigmoid: Cul de sac (rectouterine pouch) Pelvic wall/pelvic plexuses Small intestine For rectum: Anal canal/anus extraluminally Bladder for males only Cul de sac (rectouterine pouch) Ductus deferens Pelvic wall Prostate Rectovesical fascia for males only Seminal vesicle(s) Skeletal muscle of pelvic floor Vagina	T4b	T4	RE	RE
700	For all sites: Ovary(ies) Uterus For rectosigmoid: Bladder Colon via serosa Fallopian tube(s) Prostate Skeletal muscles of pelvic floor Ureter(s) Vagina For rectum: Bladder for females only Bone(s) of pelvis Cervix Perineum, perianal skin Sacrum Sacral plexus Urethra	T4b	T4	D	D
800	Further contiguous extension	T4b	T4	D	D
850	Stated as T4b with no other information on extension	T4b	T4	RE	RE
900	Stated as T4 [NOS] with no other information on extension	T4NOS	T4	RE	RE
950	No evidence of primary tumor	T0	T0	U	U
999	Unknown; extension not stated Primary tumor cannot be assessed Not documented in patient record	TX	TX	U	U

Rectum

CS Extension