Collaborative Stage

Note 1: This is a unique site-specific factor that collects information from recurrence after the initial diagnosis. The initial code is updated at the time of recurrence after the first course of globe-sparing treatment.
Note 2: Record 000 or 987 at initial diagnosis and treatment, depending on whether the initial treatment was globe-sparing or surgical enucleation.
Note 3. Change the recorded value of 000 to 010, 020, or 030 at the first recurrence in a treated eye after globe-sparing treatment. Use code 999 if recurrence is known but there is no more specific information available.

Code	Description
000	Initial diagnosis with primary globe-sparing treatment of retinoblastoma
010	Failure of primary globe-sparing treatment in unilateral retinoblastoma
020	Failure of primary globe-sparing treatment in bilateral retinoblastoma, neither eye enucleated at initial diagnosis
030	Failure of primary globe-sparing treatment in bilateral retinoblastoma, one eye only enucleated at initial diagnosis
888	OBSOLETE DATA CONVERTED V0200 See code 988 Not applicable for this site
987	Initial course of treatment was not globe-sparing for unilateral or bilateral retinoblastoma
988	Not applicable: Information not collected for this case (May include cases converted from code 888 used in CSv1 for "Not applicable" or when the item was not collected. If this item is required to derive T, N, M, or any stage, use of code 988 may result in an error.)
999	Unknown or no information Not documented in patient record

CS Site-Specific Factor 4
Primary Globe-Sparing Treatment Failure