MelanomaSkin

Note 1: According to AJCC, p. 329, "Data from the AJCC Melanoma Staging Database demonstrated a highly significant correlation with increasing mitotic rate and declining survival rates, especially within thin melanoma subgroups."
Note 2: Mitotic rate/count is assessed on primary melanomas, based on the number of mitotic figures in one square millimeter (mm) surrounding either a "hot spot" with the most mitotic figures or a field with a representative mitosis.
Note 3: Record the mitotic rate/count as documented in the pathology report. If there is more than one pathology report for the same melanoma at initial diagnosis and different mitotic counts are documented, code the highest mitotic count from any of the pathology reports. Use code 999 if there is no documentation or no mention of mitotic rate in any pathology report for the same melanoma.

Code	Description
000	0 mitoses per square millimeter (mm) Mitoses absent No mitoses present
001-010	1 - 10 mitoses/square mm (Exact measurement in mitoses/square mm) Examples: 001 1 mitosis per square mm 002 2 mitoses per square mm 010 10 mitoses per square mm
011	11 or more mitoses per square mm
988	Not applicable: Information not collected for this case (If this information is required by your standard setter, use of code 988 may result in an edit error.)
990	Stated as "less than 1 mitosis/square mm" Stated as "nonmitogenic"
991	Stated as "at least 1 mitosis/square mm" Stated as "mitogenic"
996	Mitotic rate described with denominator other than square millimeter (mm)
997	Test performed, results not in chart Test performed, quantitative results not stated
998	No histologic examination of primary site.
999	Unknown or no information Not documented in patient record

CS Site-Specific Factor 7Primary Tumor Mitotic Count/Rate