Retinoblastoma - CS Extension

Note 1: For correct calculation of derived staging fields for this schema, CS Extension and CS Site-Specific Factor 1, Extension Evaluated at Enucleation, must both be coded, whether or not an enucleation was performed. Information from enucleation is excluded from CS Extension and coded only in CS Site-Specific Factor 1.
Note 2: If both eyes are involved, code the information for the most extensively involved eye in this field, and code the information for the second eye in CS Site-Specific Factor 6.
Note 3: The mapping values for AJCC T, SS77, and SS2000 and the associated c, p, y, or a indicator (staging basis) are assigned based on the values in CS Extension (clinical extension), CS Tumor Size/Ext Eval, and CS Site-Specific Factor 1 - Extension Evaluated at Enucleation. Pathologic staging information from an enucleation always takes precedence over clinical staging, except in cases with neoadjuvant treatment where clinical disease is as extensive as or more extensive than disease at surgery.

For this site, extension is coded in two CS Fields: CS Extension (clinical extension) and CS Site-Specific Factor 1 - Extension Evaluated at Enucleation. The mapping values for the T category for AJCC stage, SS77, and SS2000 and the associated c, p, y, or a indicator are assigned based on the values in CS Extension, CS Tumor Size/Ext Eval, and CS Site-Specific Factor 1 as shown in the Special Calculation Table for AJCC T and Special Calculation Table for SEER Summary Stage.

Code	Description	TNM 7 Map	TNM 6 Map	SS77 Map	SS2000 Map
110	OBSOLETE DATA RETAINED V0200 Any eye in which the largest tumor is less than or equal to 3 mm in height AND no tumor is located closer than 1 DD (1.5mm) to the optic nerve or fovea	ERROR	T1a	L	L
120	Volume no more than two-thirds of eye AND Largest dimension not greater than 3 millimeter (mm) AND Location not closer than 1.5 mm to optic nerve or fovea AND Tumor formation: No vitreous or subretinal seeding and no subretinal fluid beyond 5 mm from base of tumor AND Retinal detachment not present Stated as T1a with no other information on extension	T1a	T1a	L	L
130	OBSOLETE DATA RETAINED V0200 All other eyes in which the tumor(s) are confined to retina regardless of location or size (up to half the volume of the eye) AND No vitreous seeding AND No retinal detachment or subretinal fluid greater than 5 mm from the base of the tumor	ERROR	T1b	L	L
140	Volume no more than two-thirds of eye AND (Largest dimension greater than 3 mm OR location closer than 1.5 mm to optic nerve or fovea) AND Tumor formation: No vitreous or subretinal seeding and no subretinal fluid beyond 5mm from base of tumor AND Retinal detachment not present Stated as T1b with no other information on extension	T1b	T1b	L	L
160	Volume no more than two-thirds of eye AND (Largest dimension greater than 3 mm OR location closer than 1.5 mm to optic nerve or fovea) AND (Tumor formation: Subretinal fluid beyond 5 mm from base of tumor OR retinal detachment present) Stated as T1c with no other information on extension	T1c	T2a	L	L
180	Volume no more than two-thirds of eye AND Tumor formation: No vitreous or subretinal seeding Stated as T1 [NOS] with no other information on extension	T1NOS	T1NOS	L	L
310	OBSOLETE DATA RETAINED V0200 Tumor confined to retina (no vitreous seeding or significant retinal detachment), NOS	ERROR	T1NOS	L	L
410	OBSOLETE DATA RETAINED V0200 Minimal tumor spread to vitreous and/or subretinal space. Fine local or diffuse vitreous seeding and/or serous retinal detachment up to total detachment may be present but no clumps, lumps, snowballs, or avascular masses are allowed in the vitreous or subretinal space. Calcium flecks in the vitreous or subretinal space are allowed. Tumor may fill up to 2/3 the volume of the eye.	ERROR	T2a	L	L
420	Volume no more than two-thirds of eye AND Tumor formation : Focal vitreous and/or subretinal seeding of fine aggregates of tumor cells but no large clumps or "snowballs" of tumor cells AND Retinal detachment may be present Stated as T2a with no other information on extension	T2a	T2a	L	L
430	OBSOLETE DATA RETAINED V0200 Massive tumor spread to vitreous and/or subretinal space. Vitreous seeding and/or subretinal implantation may consist of lumps, clumps, snowballs, or avascular tumor masses. Retinal detachment may be total. Tumor may fill up to 2/3 the volume of the eye.	ERROR	T2b	L	L
440	Volume no more than two-thirds of eye AND Tumor formation: Massive vitreous and/or subretinal seeding defined as diffuse clumps or "snowballs" of tumor cells AND Retinal detachment may be present Stated as T2b with no other information on extension	T2b	T2b	L	L
450	OBSOLETE DATA RETAINED V0200 Extension reassigned to codes 500, 520 Unsalvageable intraocular disease. Tumor fills more than 2/3 the eye No possibility of visual rehabilitation. One or more of the following are present: Tumor-associated glaucoma, either neovascular or angle closure Anterior segment extension of tumor Ciliary body extension of tumor Hyphema (significant) Massive vitreous hemorrhage Tumor in contact with lens Orbital cellulitis-like clinical presentation	ERROR	T2c	L	L
460	Volume no more than two-thirds of eye AND Tumor formation: Vitreous and/or subretinal seeding AND Retinal detachment may be present Stated as T2 [NOS] with no other information on extension	T2NOS	T2NOS	L	L
470	OBSOLETE DATA RETAINED V0200 Tumor with contiguous spread to adjacent tissues or spaces (vitreous or subretinal space), NOS	ERROR	T2NOS	L	L
500	Severe intraocular disease: Tumor occupies more than two-thirds volume of eye Stated as T3a with no other information on extension	T3a	T2c	L	L
520	Severe intraocular disease: One or more complications present including: Tumor-associated neovascular or angle closure glaucoma Tumor extension into anterior segment Hyphema (blood in anterior chamber) Vitreous hemorrhage Orbital cellulitis Stated as T3b with no other information on extension	T3b	T2c	L	L
540	Severe intraocular disease NOS Stated as T3 [NOS] with no other information on extension	T3NOS	T2c	L	L
590	OBSOLETE DATA RETAINED V0200 Invasion of optic nerve and/or optic coats, NOS	ERROR	T3	RE	RE
680	Extraocular disease detected by imaging studies: Invasion of optic nerve Stated as T4a with no other information on extension	T4a	T3	RE	RE
700	Extraocular disease detected by imaging studies: Invasion into orbit Stated as T4b with no other information on extension	T4b	T4	RE	RE
720	Extraocular disease detected by imaging studies: Intracranial extension not past optic chiasm Stated as T4c with on other information on extension	T4c	T4	D	D
740	Extraocular disease detected by imaging studies: Intracranial extension past optic chiasm Stated as T4d with no other information on extension	T4d	T4	D	D
750	OBSOLETE DATA RETAINED V0200 Extraocular tumor	ERROR	T4	RE	RE
760	Extraocular disease detected by imaging studies NOS Stated as T4 [NOS]	T4NOS	T4	RE	RE
800	OBSOLETE DATA RETAINED V0200 Further contiguous extension	ERROR	T4	D	D
950	No evidence of primary tumor	T0	T0	U	U
999	Unknown; extension not stated Primary tumor cannot be assessed Not documented in patient record	TX	TX	U	U