Thyroid - Histologies, Grade, Stage

Note: The determination of AJCC stage group from T, N, and M for thyroid depends further on histologic type, grade, and age. This table shows the selection of the appropriate version of the AJCC Stage table based on histology and grade. For papillary and follicular carcinomas, a further check on age is needed to identify the correct AJCC Stage table to be used. In the table below, "Anaplastic" maps to the table AJCC-Stage: Anaplastic; "Med", to AJCC-Stage: Medullary; and "Pap/Fol", to either AJCC Stage-Thyroid: Papillary and Follicular - Age less than 45 or AJCC Stage-Thyroid: Papillary and Follicular - Age 45 and Older. If age at diagnosis is unknown, AJCC stage is derived as unknown for papillary and follicular carcinomas.

ICD-O-3 histology code	Description	Grade	Stage Table
8020	Carcinoma, undifferentiated, NOS	1,2,3,4,9	Anaplastic
8021	Carcinoma, anaplastic, NOS	1,2,3,4,9	Anaplastic
8030	Giant cell and spindle cell carcinoma	1,2,3,4,9	Anaplastic
8031	Giant cell carcinoma	1,2,3,4,9	Anaplastic
8032	Spindle cell carcinoma	1,2,3,4,9	Anaplastic
8345	Medullary carcinoma with amyloid stroma (C73.9)	1,2,3,9	Med
8346	Mixed medullary-follicular carcinoma (C73.9)	1,2,3,9	Med
8347	Mixed medullary-papillary carcinoma (C73.9)	1,2,3,9	Med
8430	Mucoepidermoid tumor [obs]	1,2,3,9	Med
8510	Medullary carcinoma, NOS	1,2,3,9	Med
8512	Medullary carcinoma with lymphoid stroma	1,2,3,9	Med
8513	Atypical medullary carcinoma (C50._)	1,2,3,9	Med
*	Any histology in inclusion table	4	Anaplastic
*	Any histology in inclusion table	5-8	ERROR
*	ALL OTHER HISTOLOGIES IN INCLUSION TABLE	1,2,3,9	Pap/Fol