Collaborative Stage for TNM 7 - Revised 01/26/2010
Esophagus
Esophagus
C15.0-C15.5, C15.8-C15.9
- C15.0 Cervical esophagus
- C15.1 Thoracic esophagus
- C15.2 Abdominal esophagus
- C15.3 Upper third of esophagus
- C15.4 Middle third of esophagus
- C15.5 Lower third of esophagus
- C15.8 Overlapping lesion of esophagus
- C15.9 Esophagus, NOS
- The cardia/EGJ, and the proximal 5cm of the fundus and body of the stomach (C16.0-C16.2) have been moved from the Stomach chapter and added to Esophagus effective with AJCC TNM 7th Edition. A new schema EG Junction was created in CSv2 to accommodate this change.
Tumors arising at the EGJ, or arising in the stomach within 5 cm of the EGJ and crossing the EGJ are staged using the schema for EG Junction. All other cancers with a midpoint in the stomach lying more than 5 cm distal to the EGJ, or those within 5 cm of the EGJ but not extending into the EGJ or esophagus, are staged using the stomach schema.
- Anatomic Limits of Esophagus:
- Cervical Esophagus (C15.0): From the lower border of the cricoid cartilage to the thoracic inlet (suprasternal notch), about 18 cm from the incisors.
- Intrathoracic (including abdominal esophagus) (C15.1 - C15.5):
Upper thoracic portion (C15.3): From the thoracic inlet to the level of the tracheal bifurcation (18-24 cm).
Mid-thoracic portion (C15.4): From the tracheal bifurcation midway to the gastroesophageal (GE) junction (24-32 cm).
- Lower thoracic portion (C15.5: From midway between the tracheal bifurcation and the gastroesophageal junction to the GE junction, including the abdominal esophagus (C15.2) between 32-40 cm.
- Effective with AJCC TNM 7th Edition, there are separate stage groupings for squamous cell carcinoma and adenocarcinoma. Since squamous cell carcinoma typically has a poorer prognosis than adenocarcinoma, a tumor of mixed histopathologic type or a type that is not otherwise specified should be classified as squamous cell carcinoma.
- Effective with AJCC TNM 7th Edition, histologic grade is required for stage grouping.