Collaborative Stage

Note 1: Connective tissue includes adipose tissue; aponeuroses; arteries; blood vessels; bursa; connective tissue, NOS; fascia; fatty tissue; fibrous tissue; ligaments; lymphatic channels (not nodes); muscle; skeletal muscle; subcutaneous tissue; synovia; tendons; tendon sheaths; veins; and vessels, NOS. Peripheral nerves and autonomic nervous system includes: ganglia, nerve, parasympathetic nervous system, peripheral nerves, spinal nerves, sympathetic nervous system.
Note 2: SUPERFICIAL lesions are located entirely in the subcutaneous tissues without any degree of extension through the muscular fascia or into underlying muscle. (Definition from AJCC 7th edition).
Note 3: DEEP lesions are located partly or completely within one or more muscle groups within the extremity. Deep tumors may extend through the muscular fascia into the subcutaneous tissues or even to the skin but the critical criterion is location of any portion of the tumor within the muscular components of the extremity. (Definition from AJCC 7th edition).
Note 4: If a vessel has a name, for example, brachial artery or recurrent laryngeal nerve, consider it a structure (code 600).
Note 5: For tumors of the extremities and trunk ONLY, superficial lesions are defined as those not involving the superficial muscular fascia. Deep lesions are those that involve or are beneath the superficial fascia.
Note 6: According to AJCC, "All intraperitoneal visceral lesions, retroperitoneal lesions, and intrathoracic lesions, and the majority of head and neck tumors are considered deep." For coding extension of soft tissue tumors in these sites (C47.0, C47.3-5, C49.0, C49.3-5), use only codes 120, 312, 315, 320, 420, 620, 800, 950, or 990.
Note 7: Definition of Adjacent Connective Tissue: Some of the schemes for ill-defined or non-specific sites in this manual contain a code 400, adjacent connective tissue, which is defined here as the unnamed tissues that immediately surround an organ or structure containing a primary cancer. Use this code when a tumor has invaded past the outer border (capsule, serosa, or other edge) of the primary organ into the organ's surrounding supportive structures but has not invaded into larger structures or adjacent organs.

In general, these tissues do not have specific names. These tissues form the framework of many organs, provide support to hold organs in place, bind tissues and organs together, and serve as storage sites for nutrients. Blood, cartilage and bone are sometimes considered connective tissues, but in this manual they are listed separately.

* For Extension codes 100-800 the T category is assigned based on the value of CS Tumor Size as shown in the Extension Size Table for this site.
^ For Extension codes 100-800, the T category is assigned based on the value of CS Tumor Size as shown in the Extension Size Table for this site.

Code	Description	TNM 7 Map	TNM 6 Map	SS77 Map	SS2000 Map
100	Invasive tumor confined to site/tissue of origin, NOS	^	*	L	L
110	Superficial invasive tumor confined to site/tissue of origin (lesion does not involve superficial fascia)	^	*	L	L
120	Deep tumor confined to site/tissue of origin	^	*	L	L
300	Localized, NOS	^	*	L	L
302	Stated as T1a with no other information on extension	^	*	L	L
305	Stated as T2a with no other information on extension	^	*	L	L
310	Superficial: localized tumor, NOS	^	*	L	L
312	Stated as T1b with no other information on extension	^	*	L	L
315	Stated as T2b with no other information on extension	^	*	L	L
320	Deep: localized tumor, NOS	^	*	L	L
322	Stated as T1 [NOS] with no other information on extension	^	*	L	L
325	Stated as T2 [NOS] with no other information on extension	^	*	L	L
400	Adjacent connective tissue (see Note 5)	^	*	RE	RE
410	Superficial tumor involving adjacent connective tissue	^	*	RE	RE
420	Deep tumor involving adjacent connective tissue	^	*	RE	RE
600	Adjacent organs/structures including bone/cartilage (including major vessel invasion) (see Note 5)	^	*	RE	RE
610	Superficial tumor involving adjacent organs/structures including bone/cartilage (including major vessel invasion) (see Note 5)	^	*	RE	RE
620	Deep tumor involving adjacent organs/structures including bone/cartilage (including major vessel invasion) (see Note 5)	^	*	RE	RE
800	Further contiguous extension	^	*	D	D
950	No evidence of primary tumor	T0	T0	U	U
999	Unknown extension Primary tumor cannot be assessed Not documented in patient record	TX	TX	U	U

SoftTissue

CS Extension